Aurelia Yuliarty Carmila Dasor Pengarang Maxs Urias Ebenhaiser Sanam Penguji 1 Meity Marviana Laut Ketua Penguji Nemay Anggadewi Ndaong Penguji 2

Staphyloococcus aureus is a normal flora in living creatures found on the skin and mucous membranes. Staphylococcus aureus can potentially cause infections of the skin and glands. Natural ingredients that have the potential as antibacterial is Metang Wood Leaf (Lunasia amara blanco) manggarai people use metang wood leaves to treat diabetes and wounds on the skin. This study aims to determine the compound contect of 70% ethanol exctract of metang wood leaves and its antibacterial activity against S. Aureus. This study used four replications and there were three variations of the 70% ethanol extract concentration, namely 5%, 10%, and 20%. Data analysis in this study employed One-Way Anova followed by normality test and homogeneity test with 95% confidence level (a = 0.05). The results revealed that the inhibition zones resulting from concentrations of 5%, 10%, and 20% had different diameter values and had the same average antibacterial strength, namely the strong category because the range of inhibition zones formed is 9.525 mm to 14.65 mm. The result of the one-way Anova test was a significance of p = 0.397. There was no significant difference in each concentration of metang wood leaf extract with p value> 0.05. The use of metang wood extract had a smaller inhibitory power than the use of the antibiotic ciprofloxacin, but the use of metang leaf wood extract has been shown to inhibit S. aureus bacteria. This study concluded that the leaves of metang leaf wood (Lunasia amara blanco) have been shown to contain alkaloids, flavonoids, saponins and terpenoids, and antibacterial compounds to the growth of Staphylococcus aureus. Keywords : Lunasia amara blanco, Staphylocoocus aureus, Ethanol